Nanotechnology Applications in Neuroscience: Advances, Opportunities and Challenges
نویسندگان
چکیده
Metrenin milyarda birine eşit olan “nanometre”, 21. yüzyılın ikinci yarısında yaşamın her alanında duyulmaya başlamıştır. Santral sinir sistemi hastalıklarının insidansında gözlenen artış, bu alanda yeni tedavi ve profilaksi yöntemlerine ihtiyacı gündeme getirerek nanoteknoloji ve sinir bilim konseptlerini biraraya getirmiştir. Bu durumun temel sebebi, kan-beyin bariyerinin (KBB) yapısının konvansiyonel ilaç uygulamalarını etkisiz bırakmış olmasıdır. Nanoteknolojik ürünler, uyunçta ve biyoyararlanımda artma, ilaç moleküllerinin KBB’ye penetrasyonunu kolaylaştırma ve görülen yan etkilerde azalma sağlamıştır. Bu derleme, KBB’den geçişi kolaylaştıran bazı tedavi yaklaşımları ile kullanımı fark yaratan önemli nanoteknolojik ve mikro-elektro mekanik sistem örneklerini özetlemektedir. Ayrıca, bazı ürünlerin uygulanmasındaki invazif prosedürler ile mikroçip ve nano cihazların kullanımı hakkında temel tartışma konularından da bahsedilmiştir.
منابع مشابه
Glucose-based Biofuel Cells: Nanotechnology as a Vital Science in Biofuel Cells Performance
Nanotechnology has opened up new opportunities for the design of nanoscale electronic devices suitable for developing high-performance biofuel cells. Glucose-based biofuel cells as green energy sources can be a powerful tool in the service of small-scale power source technology as it provides a latent potential to supply power for various implantable medical electronic devices. By using physiol...
متن کاملRecommendations of the National Heart, Lung, and Blood Institute Nanotechnology Working Group.
Recent rapid advances in nanotechnology and nanoscience offer a wealth of new opportunities for diagnosis and therapy of cardiovascular, pulmonary, and hematologic diseases and sleep disorders. To review the challenges and opportunities offered by these nascent fields, the National Heart, Lung, and Blood Institute convened a Working Group on Nanotechnology. Working Group participants discussed ...
متن کاملThe Nanopharmacology and Nanotoxicology of Nanomaterials: New Opportunities and Challenges.
The very dynamic growth of nanotechnology, nanomaterials (sized 1-100 nm) and their medical applications over the past 10 years has promised to add a new impetus to the diagnostics and therapeutics of a wide range of human pathologies, including cancer, cardiovascular diseases and diseases of the central nervous system. This growth in nanomedicine also fuels advances in bioengineering, regenera...
متن کاملNanotechnology and Neuroscience Convergence: A Novel Tool for Neurotransmitters Monitoring
Since neurotransmitters significantly influence the brain activity, our understanding of the human brain will remain imperfect until all aspects relating to them become clear. One of the key challenges in neuroscience researches and therapies is elucidating the mechanisms by which the neurotransmitter release take place and is regulated in quantity and in time. Despite the enormous number of st...
متن کاملInnovations in nanotechnology for water treatment
Important challenges in the global water situation, mainly resulting from worldwide population growth and climate change, require novel innovative water technologies in order to ensure a supply of drinking water and reduce global water pollution. Against this background, the adaptation of highly advanced nanotechnology to traditional process engineering offers new opportunities in technological...
متن کامل